Tranylcypromine en es it fr

Tranylcypromine Brand names, Tranylcypromine Analogs

Tranylcypromine Brand Names Mixture

  • No information avaliable

Tranylcypromine Chemical_Formula


Tranylcypromine RX_link

Tranylcypromine fda sheet

Tranylcypromine FDA

Tranylcypromine msds (material safety sheet)

Tranylcypromine MSDS

Tranylcypromine Synthesis Reference

No information avaliable

Tranylcypromine Molecular Weight

133.19 g/mol

Tranylcypromine Melting Point

79-80 oC at 1.50E+00 mm Hg

Tranylcypromine H2O Solubility

4.86E+004 mg/L

Tranylcypromine State


Tranylcypromine LogP


Tranylcypromine Dosage Forms

Tablets (10 mg, for oral administration)

Tranylcypromine Indication

For the treatment of major depressive episode without melancholia.

Tranylcypromine Pharmacology

Tranylcypromine belongs to a class of antidepressants called monoamine oxidase inhibitors (MAOIs). Tranylcypromine is a non-hydrazine monoamine oxidase inhibitor with a rapid onset of activity. It increases the concentration of epinephrine, norepinephrine, and serotonin in storage sites throughout the nervous system and, in theory, this increased concentration of monoamines in the brain stem is the basis for its antidepressant activity.

Tranylcypromine Absorption

No information avaliable

Tranylcypromine side effects and Toxicity

In overdosage, some patients exhibit insomnia, restlessness and anxiety, progressing in severe cases to agitation, mental confusion and incoherence. Hypotension, dizziness, weakness and drowsiness may occur, progressing in severe cases to extreme dizziness and shock. A few patients have displayed hypertension with severe headache and other symptoms. Rare instances have been reported in which hypertension was accompanied by twitching or myoclonic fibrillation of skeletal muscles with hyperpyrexia, sometimes progressing to generalized rigidity and coma.

Tranylcypromine Patient Information

Tranylcypromine Organisms Affected

Humans and other mammals