Parnate
Parnate Brand names, Parnate Analogs
Parnate Brand Names Mixture
- No information avaliable
Parnate Chemical_Formula
C9H11N
Parnate RX_link
http://www.rxlist.com/cgi/generic2/tranylcypromine.htm
Parnate fda sheet
Parnate msds (material safety sheet)
Parnate Synthesis Reference
No information avaliable
Parnate Molecular Weight
133.19 g/mol
Parnate Melting Point
79-80 oC at 1.50E+00 mm Hg
Parnate H2O Solubility
4.86E+004 mg/L
Parnate State
Solid
Parnate LogP
1.434
Parnate Dosage Forms
Tablets (10 mg, for oral administration)
Parnate Indication
For the treatment of major depressive episode without melancholia.
Parnate Pharmacology
Tranylcypromine belongs to a class of antidepressants called monoamine oxidase inhibitors (MAOIs). Tranylcypromine is a non-hydrazine monoamine oxidase inhibitor with a rapid onset of activity. It increases the concentration of epinephrine, norepinephrine, and serotonin in storage sites throughout the nervous system and, in theory, this increased concentration of monoamines in the brain stem is the basis for its antidepressant activity.
Parnate Absorption
No information avaliable
Parnate side effects and Toxicity
In overdosage, some patients exhibit insomnia, restlessness and anxiety, progressing in severe cases to agitation, mental confusion and incoherence. Hypotension, dizziness, weakness and drowsiness may occur, progressing in severe cases to extreme dizziness and shock. A few patients have displayed hypertension with severe headache and other symptoms. Rare instances have been reported in which hypertension was accompanied by twitching or myoclonic fibrillation of skeletal muscles with hyperpyrexia, sometimes progressing to generalized rigidity and coma.
Parnate Patient Information
Parnate Organisms Affected
Humans and other mammals
