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Parnate Brand names, Parnate Analogs

Parnate Brand Names Mixture

  • No information avaliable

Parnate Chemical_Formula


Parnate RX_link

Parnate fda sheet

Parnate FDA

Parnate msds (material safety sheet)

Parnate MSDS

Parnate Synthesis Reference

No information avaliable

Parnate Molecular Weight

133.19 g/mol

Parnate Melting Point

79-80 oC at 1.50E+00 mm Hg

Parnate H2O Solubility

4.86E+004 mg/L

Parnate State


Parnate LogP


Parnate Dosage Forms

Tablets (10 mg, for oral administration)

Parnate Indication

For the treatment of major depressive episode without melancholia.

Parnate Pharmacology

Tranylcypromine belongs to a class of antidepressants called monoamine oxidase inhibitors (MAOIs). Tranylcypromine is a non-hydrazine monoamine oxidase inhibitor with a rapid onset of activity. It increases the concentration of epinephrine, norepinephrine, and serotonin in storage sites throughout the nervous system and, in theory, this increased concentration of monoamines in the brain stem is the basis for its antidepressant activity.

Parnate Absorption

No information avaliable

Parnate side effects and Toxicity

In overdosage, some patients exhibit insomnia, restlessness and anxiety, progressing in severe cases to agitation, mental confusion and incoherence. Hypotension, dizziness, weakness and drowsiness may occur, progressing in severe cases to extreme dizziness and shock. A few patients have displayed hypertension with severe headache and other symptoms. Rare instances have been reported in which hypertension was accompanied by twitching or myoclonic fibrillation of skeletal muscles with hyperpyrexia, sometimes progressing to generalized rigidity and coma.

Parnate Patient Information

Parnate Organisms Affected

Humans and other mammals