Transamine
Transamine Brand names, Transamine Analogs
Transamine Brand Names Mixture
- No information avaliable
Transamine Chemical_Formula
C9H11N
Transamine RX_link
http://www.rxlist.com/cgi/generic2/tranylcypromine.htm
Transamine fda sheet
Transamine msds (material safety sheet)
Transamine Synthesis Reference
No information avaliable
Transamine Molecular Weight
133.19 g/mol
Transamine Melting Point
79-80 oC at 1.50E+00 mm Hg
Transamine H2O Solubility
4.86E+004 mg/L
Transamine State
Solid
Transamine LogP
1.434
Transamine Dosage Forms
Tablets (10 mg, for oral administration)
Transamine Indication
For the treatment of major depressive episode without melancholia.
Transamine Pharmacology
Tranylcypromine belongs to a class of antidepressants called monoamine oxidase inhibitors (MAOIs). Tranylcypromine is a non-hydrazine monoamine oxidase inhibitor with a rapid onset of activity. It increases the concentration of epinephrine, norepinephrine, and serotonin in storage sites throughout the nervous system and, in theory, this increased concentration of monoamines in the brain stem is the basis for its antidepressant activity.
Transamine Absorption
No information avaliable
Transamine side effects and Toxicity
In overdosage, some patients exhibit insomnia, restlessness and anxiety, progressing in severe cases to agitation, mental confusion and incoherence. Hypotension, dizziness, weakness and drowsiness may occur, progressing in severe cases to extreme dizziness and shock. A few patients have displayed hypertension with severe headache and other symptoms. Rare instances have been reported in which hypertension was accompanied by twitching or myoclonic fibrillation of skeletal muscles with hyperpyrexia, sometimes progressing to generalized rigidity and coma.
Transamine Patient Information
Transamine Organisms Affected
Humans and other mammals
