Therapav
Brand names,
Therapav
Analogs
Therapav
Brand Names Mixture
Therapav
Chemical_Formula
C20H21NO4
Therapav
RX_link
http://www.rxlist.com/cgi/generic/papaverine.htm
Therapav
fda sheet
Therapav
msds (material safety sheet)
Therapav
Synthesis Reference
No information avaliable
Therapav
Molecular Weight
339.385 g/mol
Therapav
Melting Point
No information avaliable
Therapav
H2O Solubility
No information avaliable
Therapav
State
Solid
Therapav
LogP
3.72
Therapav
Dosage Forms
Liquid
Therapav
Indication
For the treatment of impotence
Therapav
Pharmacology
Papaverine is a nonxanthine phosphodiesterase inhibitor for the relief of cerebral and peripheral ischemia associated with arterial spasm and myocardial ischemia complicated by arrhythmias. The main actions of Papaverine are exerted on cardiac and smooth muscle. Like qathidine, Papaverine acts directly on the heart muscle to depress conduction and prolong the refractory period. Papaverine relaxes various smooth muscles. This relaxation may be prominent if spasm exists. The muscle cell is not paralyzed by Papaverine and still responds to drugs and other stimuli causing contraction. The antispasmodic effect is a direct one, and unrelated to muscle innervation. Papaverine is practically devoid of effects on the central nervous system. Papaverine relaxes the smooth musculature of the larger blood vessels, especially coronary, systemic peripheral, and pulmonary arteries.
Therapav
Absorption
No information avaliable
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side effects and Toxicity
No information avaliable
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Patient Information
No information avaliable
Therapav
Organisms Affected
Humans and other mammals