Pap H
Brand names,
Pap H
Analogs
Pap H
Brand Names Mixture
Pap H
Chemical_Formula
C20H21NO4
Pap H
RX_link
http://www.rxlist.com/cgi/generic/papaverine.htm
Pap H
fda sheet
Pap H
msds (material safety sheet)
Pap H
Synthesis Reference
No information avaliable
Pap H
Molecular Weight
339.385 g/mol
Pap H
Melting Point
No information avaliable
Pap H
H2O Solubility
No information avaliable
Pap H
State
Solid
Pap H
LogP
3.72
Pap H
Dosage Forms
Liquid
Pap H
Indication
For the treatment of impotence
Pap H
Pharmacology
Papaverine is a nonxanthine phosphodiesterase inhibitor for the relief of cerebral and peripheral ischemia associated with arterial spasm and myocardial ischemia complicated by arrhythmias. The main actions of Papaverine are exerted on cardiac and smooth muscle. Like qathidine, Papaverine acts directly on the heart muscle to depress conduction and prolong the refractory period. Papaverine relaxes various smooth muscles. This relaxation may be prominent if spasm exists. The muscle cell is not paralyzed by Papaverine and still responds to drugs and other stimuli causing contraction. The antispasmodic effect is a direct one, and unrelated to muscle innervation. Papaverine is practically devoid of effects on the central nervous system. Papaverine relaxes the smooth musculature of the larger blood vessels, especially coronary, systemic peripheral, and pulmonary arteries.
Pap H
Absorption
No information avaliable
Pap H
side effects and Toxicity
No information avaliable
Pap H
Patient Information
No information avaliable
Pap H
Organisms Affected
Humans and other mammals