Papaverine, Hydrochloride
Brand names,
Papaverine, Hydrochloride
Analogs
Papaverine, Hydrochloride
Brand Names Mixture
Papaverine, Hydrochloride
Chemical_Formula
C20H21NO4
Papaverine, Hydrochloride
RX_link
http://www.rxlist.com/cgi/generic/papaverine.htm
Papaverine, Hydrochloride
fda sheet
Papaverine, Hydrochloride
msds (material safety sheet)
Papaverine, Hydrochloride
Synthesis Reference
No information avaliable
Papaverine, Hydrochloride
Molecular Weight
339.385 g/mol
Papaverine, Hydrochloride
Melting Point
No information avaliable
Papaverine, Hydrochloride
H2O Solubility
No information avaliable
Papaverine, Hydrochloride
State
Solid
Papaverine, Hydrochloride
LogP
3.72
Papaverine, Hydrochloride
Dosage Forms
Liquid
Papaverine, Hydrochloride
Indication
For the treatment of impotence
Papaverine, Hydrochloride
Pharmacology
Papaverine is a nonxanthine phosphodiesterase inhibitor for the relief of cerebral and peripheral ischemia associated with arterial spasm and myocardial ischemia complicated by arrhythmias. The main actions of Papaverine are exerted on cardiac and smooth muscle. Like qathidine, Papaverine acts directly on the heart muscle to depress conduction and prolong the refractory period. Papaverine relaxes various smooth muscles. This relaxation may be prominent if spasm exists. The muscle cell is not paralyzed by Papaverine and still responds to drugs and other stimuli causing contraction. The antispasmodic effect is a direct one, and unrelated to muscle innervation. Papaverine is practically devoid of effects on the central nervous system. Papaverine relaxes the smooth musculature of the larger blood vessels, especially coronary, systemic peripheral, and pulmonary arteries.
Papaverine, Hydrochloride
Absorption
No information avaliable
Papaverine, Hydrochloride
side effects and Toxicity
No information avaliable
Papaverine, Hydrochloride
Patient Information
No information avaliable
Papaverine, Hydrochloride
Organisms Affected
Humans and other mammals