Tequin
Brand names,
Tequin
Analogs
Tequin
Brand Names Mixture
- GyneCure Vaginal Ointment Tandempak 6.5% (Tioconazole + other)
- GyneCure Vaginal Ovules Tandempak (Tioconazole + other)
Tequin
Chemical_Formula
C19H22FN3O4
Tequin
RX_link
http://www.rxlist.com/cgi/generic3/gatifloxacin.htm
Tequin
fda sheet
Tequin
msds (material safety sheet)
Tequin
Synthesis Reference
No information avaliable
Tequin
Molecular Weight
375.394 g/mol
Tequin
Melting Point
182-185 oC
Tequin
H2O Solubility
60 mg/mL (at pH 4)
Tequin
State
Solid
Tequin
LogP
1.801
Tequin
Dosage Forms
Liquid; Solution; Tablet
Tequin
Indication
For the treatment of bronchitis, sinusitis, community-acquired pneumonia, and skin infections (abscesses, wounds) caused by S. pneumoniae, H. influenzae, S. aureus, M. pneumoniae, C. pneumoniae, L. pneumophila, S. pyogenes
Tequin
Pharmacology
Gatifloxacin is a synthetic broad-spectrum 8-methoxyfluoroquinolone antibacterial agent for oral or intravenous administration. is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase, which allows the untwisting required to replicate one DNA double helix into two. Notably the drug has 100 times higher affinity for bacterial DNA gyrase than for mammalian. Gatifloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.
Tequin
Absorption
Well absorbed from the gastrointestinal tract after oral administration with absolute bioavailability of gatifloxacin is 96%
Tequin
side effects and Toxicity
No information avaliable
Tequin
Patient Information
No information avaliable
Tequin
Organisms Affected
Enteric bacteria and other eubacteria