Zymar
Zymar Brand names, Zymar Analogs
Zymar Brand Names Mixture
- GyneCure Vaginal Ointment Tandempak 6.5% (Tioconazole + other)
- GyneCure Vaginal Ovules Tandempak (Tioconazole + other)
Zymar Chemical_Formula
C19H22FN3O4
Zymar RX_link
http://www.rxlist.com/cgi/generic3/gatifloxacin.htm
Zymar fda sheet
Zymar msds (material safety sheet)
Zymar Synthesis Reference
No information avaliable
Zymar Molecular Weight
375.394 g/mol
Zymar Melting Point
182-185 oC
Zymar H2O Solubility
60 mg/mL (at pH 4)
Zymar State
Solid
Zymar LogP
1.801
Zymar Dosage Forms
Liquid; Solution; Tablet
Zymar Indication
For the treatment of bronchitis, sinusitis, community-acquired pneumonia, and skin infections (abscesses, wounds) caused by S. pneumoniae, H. influenzae, S. aureus, M. pneumoniae, C. pneumoniae, L. pneumophila, S. pyogenes
Zymar Pharmacology
Gatifloxacin is a synthetic broad-spectrum 8-methoxyfluoroquinolone antibacterial agent for oral or intravenous administration. is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase, which allows the untwisting required to replicate one DNA double helix into two. Notably the drug has 100 times higher affinity for bacterial DNA gyrase than for mammalian. Gatifloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.
Zymar Absorption
Well absorbed from the gastrointestinal tract after oral administration with absolute bioavailability of gatifloxacin is 96%
Zymar side effects and Toxicity
No information avaliable
Zymar Patient Information
No information avaliable
Zymar Organisms Affected
Enteric bacteria and other eubacteria
