Telithromycin
Brand names,
Telithromycin
Analogs
Telithromycin
Brand Names Mixture
Telithromycin
Chemical_Formula
C43H65N5O10
Telithromycin
RX_link
http://www.rxlist.com/cgi/generic3/ketek.htm
Telithromycin
fda sheet
Telithromycin
msds (material safety sheet)
Telithromycin
Synthesis Reference
No information avaliable
Telithromycin
Molecular Weight
812.004 g/mol
Telithromycin
Melting Point
176-188 oC
Telithromycin
H2O Solubility
300 mg/L
Telithromycin
State
Solid
Telithromycin
LogP
3.731
Telithromycin
Dosage Forms
Tablet
Telithromycin
Indication
For the treatment of Pneumococcal infection, acute sinusitis, acute bacterial tonsillitis, acute bronchitis and bronchiolitis, lower respiratory tract infection and lobar (pneumococcal) pneumonia.
Telithromycin
Pharmacology
Telithromycin is a macrolide antibiotic which has an antimicrobial spectrum similar or slightly wider to that of penicillin, and is often used for people who have an allergy to penicillins. For respiratory tract infections, it has better coverage of atypical organisms, including mycoplasma. It is also used to treat outbreaks of chlamydia, syphilis, and gonorrhea. Telithromycin prevents bacteria from growing, by interfering with their protein synthesis. Telithromycin binds to the subunit 50S of the bacterial ribosome, and thus inhibits the translocation of peptides.
Telithromycin
Absorption
No information avaliable
Telithromycin
side effects and Toxicity
LD50>2000 mg/kg (PO in rats)
Telithromycin
Patient Information
PATIENT INFORMATION
Please follow the link below for more information and the links in Drug_reference region in DrugBank.
http://www.rxlist.com/cgi/generic3/ketek_pi.htm
Telithromycin
Organisms Affected
Enteric bacteria and other eubacteria