Ketek (TN)
Brand names,
Ketek (TN)
Analogs
Ketek (TN)
Brand Names Mixture
Ketek (TN)
Chemical_Formula
C43H65N5O10
Ketek (TN)
RX_link
http://www.rxlist.com/cgi/generic3/ketek.htm
Ketek (TN)
fda sheet
Ketek (TN)
msds (material safety sheet)
Ketek (TN)
Synthesis Reference
No information avaliable
Ketek (TN)
Molecular Weight
812.004 g/mol
Ketek (TN)
Melting Point
176-188 oC
Ketek (TN)
H2O Solubility
300 mg/L
Ketek (TN)
State
Solid
Ketek (TN)
LogP
3.731
Ketek (TN)
Dosage Forms
Tablet
Ketek (TN)
Indication
For the treatment of Pneumococcal infection, acute sinusitis, acute bacterial tonsillitis, acute bronchitis and bronchiolitis, lower respiratory tract infection and lobar (pneumococcal) pneumonia.
Ketek (TN)
Pharmacology
Telithromycin is a macrolide antibiotic which has an antimicrobial spectrum similar or slightly wider to that of penicillin, and is often used for people who have an allergy to penicillins. For respiratory tract infections, it has better coverage of atypical organisms, including mycoplasma. It is also used to treat outbreaks of chlamydia, syphilis, and gonorrhea. Telithromycin prevents bacteria from growing, by interfering with their protein synthesis. Telithromycin binds to the subunit 50S of the bacterial ribosome, and thus inhibits the translocation of peptides.
Ketek (TN)
Absorption
No information avaliable
Ketek (TN)
side effects and Toxicity
LD50>2000 mg/kg (PO in rats)
Ketek (TN)
Patient Information
PATIENT INFORMATION
Please follow the link below for more information and the links in Drug_reference region in DrugBank.
http://www.rxlist.com/cgi/generic3/ketek_pi.htm
Ketek (TN)
Organisms Affected
Enteric bacteria and other eubacteria