Ketek
Brand names,
Ketek
Analogs
Ketek
Brand Names Mixture
Ketek
Chemical_Formula
C43H65N5O10
Ketek
RX_link
http://www.rxlist.com/cgi/generic3/ketek.htm
Ketek
fda sheet
Ketek
msds (material safety sheet)
Ketek
Synthesis Reference
No information avaliable
Ketek
Molecular Weight
812.004 g/mol
Ketek
Melting Point
176-188 oC
Ketek
H2O Solubility
300 mg/L
Ketek
State
Solid
Ketek
LogP
3.731
Ketek
Dosage Forms
Tablet
Ketek
Indication
For the treatment of Pneumococcal infection, acute sinusitis, acute bacterial tonsillitis, acute bronchitis and bronchiolitis, lower respiratory tract infection and lobar (pneumococcal) pneumonia.
Ketek
Pharmacology
Telithromycin is a macrolide antibiotic which has an antimicrobial spectrum similar or slightly wider to that of penicillin, and is often used for people who have an allergy to penicillins. For respiratory tract infections, it has better coverage of atypical organisms, including mycoplasma. It is also used to treat outbreaks of chlamydia, syphilis, and gonorrhea. Telithromycin prevents bacteria from growing, by interfering with their protein synthesis. Telithromycin binds to the subunit 50S of the bacterial ribosome, and thus inhibits the translocation of peptides.
Ketek
Absorption
No information avaliable
Ketek
side effects and Toxicity
LD50>2000 mg/kg (PO in rats)
Ketek
Patient Information
PATIENT INFORMATION
Please follow the link below for more information and the links in Drug_reference region in DrugBank.
http://www.rxlist.com/cgi/generic3/ketek_pi.htm
Ketek
Organisms Affected
Enteric bacteria and other eubacteria