Synestrol
Brand names,
Synestrol
Analogs
Synestrol
Brand Names Mixture
Synestrol
Chemical_Formula
C18H18O2
Synestrol
RX_link
http://www.rxlist.com/cgi/generic2/diene.htm
Synestrol
fda sheet
Synestrol
msds (material safety sheet)
Synestrol
Synthesis Reference
No information avaliable
Synestrol
Molecular Weight
266.334 g/mol
Synestrol
Melting Point
227.5 oC
Synestrol
H2O Solubility
3 mg/L
Synestrol
State
Solid
Synestrol
LogP
4.498
Synestrol
Dosage Forms
Cream (0.01%)
Synestrol
Indication
For use in the treatment of atrophic vaginitis and kraurosis vulvae.
Synestrol
Pharmacology
Dienestrol is a synthetic, non-steroidal estrogen. Estrogens passively diffuse into target cells of responsive tissues, complex with the estrogen receptors, and enter the cell's nucleus to initiate or enhance gene transcription of protein synthesis after binding to DNA.
Synestrol
Absorption
Systemic absorption and mode of action of dienestrol are undetermined.
Synestrol
side effects and Toxicity
Symptoms of overdose include nausea and vomiting, and withdrawal bleeding may occur in females.
Synestrol
Patient Information
Synestrol
Organisms Affected
Humans and other mammals