Dehydrostilboestrol
Brand names,
Dehydrostilboestrol
Analogs
Dehydrostilboestrol
Brand Names Mixture
Dehydrostilboestrol
Chemical_Formula
C18H18O2
Dehydrostilboestrol
RX_link
http://www.rxlist.com/cgi/generic2/diene.htm
Dehydrostilboestrol
fda sheet
Dehydrostilboestrol
msds (material safety sheet)
Dehydrostilboestrol
Synthesis Reference
No information avaliable
Dehydrostilboestrol
Molecular Weight
266.334 g/mol
Dehydrostilboestrol
Melting Point
227.5 oC
Dehydrostilboestrol
H2O Solubility
3 mg/L
Dehydrostilboestrol
State
Solid
Dehydrostilboestrol
LogP
4.498
Dehydrostilboestrol
Dosage Forms
Cream (0.01%)
Dehydrostilboestrol
Indication
For use in the treatment of atrophic vaginitis and kraurosis vulvae.
Dehydrostilboestrol
Pharmacology
Dienestrol is a synthetic, non-steroidal estrogen. Estrogens passively diffuse into target cells of responsive tissues, complex with the estrogen receptors, and enter the cell's nucleus to initiate or enhance gene transcription of protein synthesis after binding to DNA.
Dehydrostilboestrol
Absorption
Systemic absorption and mode of action of dienestrol are undetermined.
Dehydrostilboestrol
side effects and Toxicity
Symptoms of overdose include nausea and vomiting, and withdrawal bleeding may occur in females.
Dehydrostilboestrol
Patient Information
Dehydrostilboestrol
Organisms Affected
Humans and other mammals