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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C18H18O2
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RX_link
http://www.rxlist.com/cgi/generic2/diene.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
266.334 g/mol
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Melting Point
227.5 oC
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H2O Solubility
3 mg/L
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State
Solid
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LogP
4.498
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Dosage Forms
Cream (0.01%)
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Indication
For use in the treatment of atrophic vaginitis and kraurosis vulvae.
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Pharmacology
Dienestrol is a synthetic, non-steroidal estrogen. Estrogens passively diffuse into target cells of responsive tissues, complex with the estrogen receptors, and enter the cell's nucleus to initiate or enhance gene transcription of protein synthesis after binding to DNA.
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Absorption
Systemic absorption and mode of action of dienestrol are undetermined.
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side effects and Toxicity
Symptoms of overdose include nausea and vomiting, and withdrawal bleeding may occur in females.
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Patient Information
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Organisms Affected
Humans and other mammals