Romglizone

• Vasodilator Agents
• Hypoglycemic Agents
• Platelet Aggregation Inhibitors
• Fibrinolytic Agents
• Antineoplastic Agents
• ATC:A10BG01

• Mesylate
• Noscal
• Prelay
• Rezulin
• Romglizone
• Troglitazone [USAN:BAN:INN]

• No information avaliable

C₂₄H₂₇NO₅S

http://www.rxlist.com/cgi/generic/troglitazone.htm

Romglizone FDA

No information avaliable

441.541 g/mol

184-186 ^oC

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Solid

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For the treatment of Type II diabetes mellitus

Troglitazone is an oral antihyperglycemic agent which acts primarily by decreasing insulin resistance. Troglitazone is used in the management of type II diabetes (noninsulin-dependent diabetes mellitus (NIDDM) also known as adult-onset diabetes). It improves sensitivity to insulin in muscle and adipose tissue and inhibits hepatic gluconeogenesis. Troglitazone is not chemically or functionally related to either the sulfonylureas, the biguanides, or the g-glucosidase inhibitors. Troglitazone may be used concomitantly with a sulfonylurea or insulin to improve glycemic control.

Absorbed rapidly. Food increases the extent of absorption by 30% to 85%.

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PATIENT INFORMATION

Follow the links

http://www.rxlist.com/cgi/generic/troglitazone_pi.htm

http://www.rxlist.com/cgi/generic/troglitazone_wcp.htm

http://www.drugs.com/cons/Troglitazone.html

Humans and other mammals