Rezulin
Brand names,
Rezulin
Analogs
Rezulin
Brand Names Mixture
Rezulin
Chemical_Formula
C24H27NO5S
Rezulin
RX_link
http://www.rxlist.com/cgi/generic/troglitazone.htm
Rezulin
fda sheet
Rezulin
msds (material safety sheet)
Rezulin
Synthesis Reference
No information avaliable
Rezulin
Molecular Weight
441.541 g/mol
Rezulin
Melting Point
184-186 oC
Rezulin
H2O Solubility
No information avaliable
Rezulin
State
Solid
Rezulin
LogP
No information avaliable
Rezulin
Dosage Forms
No information avaliable
Rezulin
Indication
For the treatment of Type II diabetes mellitus
Rezulin
Pharmacology
Troglitazone is an oral antihyperglycemic agent which acts primarily by decreasing insulin resistance. Troglitazone is used in the management of type II diabetes (noninsulin-dependent diabetes mellitus (NIDDM) also known as adult-onset diabetes). It improves sensitivity to insulin in muscle and adipose tissue and inhibits hepatic gluconeogenesis. Troglitazone is not chemically or functionally related to either the sulfonylureas, the biguanides, or the g-glucosidase inhibitors. Troglitazone may be used concomitantly with a sulfonylurea or insulin to improve glycemic control.
Rezulin
Absorption
Absorbed rapidly. Food increases the extent of absorption by 30% to 85%.
Rezulin
side effects and Toxicity
No information avaliable
Rezulin
Patient Information
PATIENT INFORMATION
Follow the links
http://www.rxlist.com/cgi/generic/troglitazone_pi.htm
http://www.rxlist.com/cgi/generic/troglitazone_wcp.htm
http://www.drugs.com/cons/Troglitazone.html
Rezulin
Organisms Affected
Humans and other mammals