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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C24H27NO5S
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RX_link
http://www.rxlist.com/cgi/generic/troglitazone.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
441.541 g/mol
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Melting Point
184-186 oC
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H2O Solubility
No information avaliable
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State
Solid
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LogP
No information avaliable
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Dosage Forms
No information avaliable
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Indication
For the treatment of Type II diabetes mellitus
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Pharmacology
Troglitazone is an oral antihyperglycemic agent which acts primarily by decreasing insulin resistance. Troglitazone is used in the management of type II diabetes (noninsulin-dependent diabetes mellitus (NIDDM) also known as adult-onset diabetes). It improves sensitivity to insulin in muscle and adipose tissue and inhibits hepatic gluconeogenesis. Troglitazone is not chemically or functionally related to either the sulfonylureas, the biguanides, or the g-glucosidase inhibitors. Troglitazone may be used concomitantly with a sulfonylurea or insulin to improve glycemic control.
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Absorption
Absorbed rapidly. Food increases the extent of absorption by 30% to 85%.
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side effects and Toxicity
No information avaliable
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Patient Information
PATIENT INFORMATION
Follow the links
http://www.rxlist.com/cgi/generic/troglitazone_pi.htm
http://www.rxlist.com/cgi/generic/troglitazone_wcp.htm
http://www.drugs.com/cons/Troglitazone.html
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Organisms Affected
Humans and other mammals