Remoxipride
Remoxipride Brand names, Remoxipride Analogs
Remoxipride Brand Names Mixture
- No information avaliable
Remoxipride Chemical_Formula
C16H23BrN2O3
Remoxipride RX_link
No information avaliable
Remoxipride fda sheet
Remoxipride msds (material safety sheet)
Remoxipride Synthesis Reference
No information avaliable
Remoxipride Molecular Weight
371.269 g/mol
Remoxipride Melting Point
No information avaliable
Remoxipride H2O Solubility
74 mg/L
Remoxipride State
Solid
Remoxipride LogP
3.511
Remoxipride Dosage Forms
Tablet
Remoxipride Indication
For the treatment of schizophrenia.
Remoxipride Pharmacology
Remoxipride, a substituted benzamide, is a selective D2 receptor antagonist. It has been shown to be effective in the treatment of schizophrenia. Some antipsychotics block domapinergic receptors as well as cholinergic, noradrenergic and histaminergic receptors. Remoxipride was developed to act specifically on the dopamine D2 receptor. As a consequence, several undesired side effects can occur. Patients often feel they are not taking any antipsychotic drug. It has a potent affinity for the sigma receptor, but it is unclear whether it is a sigma agonist or antagonist. The contribution of this property to its clinical profile is unknown. Blocking the D2 dopamine receptor is known to cause relapse in patients that have achieved remission from depression, and such blocking also counteracts the effectiveness of SSRI medication.
Remoxipride Absorption
Rapidly absorbed. Absolute bioavailability is 90%.
Remoxipride side effects and Toxicity
No information avaliable
Remoxipride Patient Information
No information avaliable
Remoxipride Organisms Affected
Humans and other mammals
