Romoxipride
Romoxipride Brand names, Romoxipride Analogs
Romoxipride Brand Names Mixture
- No information avaliable
Romoxipride Chemical_Formula
C16H23BrN2O3
Romoxipride RX_link
No information avaliable
Romoxipride fda sheet
Romoxipride msds (material safety sheet)
Romoxipride Synthesis Reference
No information avaliable
Romoxipride Molecular Weight
371.269 g/mol
Romoxipride Melting Point
No information avaliable
Romoxipride H2O Solubility
74 mg/L
Romoxipride State
Solid
Romoxipride LogP
3.511
Romoxipride Dosage Forms
Tablet
Romoxipride Indication
For the treatment of schizophrenia.
Romoxipride Pharmacology
Remoxipride, a substituted benzamide, is a selective D2 receptor antagonist. It has been shown to be effective in the treatment of schizophrenia. Some antipsychotics block domapinergic receptors as well as cholinergic, noradrenergic and histaminergic receptors. Remoxipride was developed to act specifically on the dopamine D2 receptor. As a consequence, several undesired side effects can occur. Patients often feel they are not taking any antipsychotic drug. It has a potent affinity for the sigma receptor, but it is unclear whether it is a sigma agonist or antagonist. The contribution of this property to its clinical profile is unknown. Blocking the D2 dopamine receptor is known to cause relapse in patients that have achieved remission from depression, and such blocking also counteracts the effectiveness of SSRI medication.
Romoxipride Absorption
Rapidly absorbed. Absolute bioavailability is 90%.
Romoxipride side effects and Toxicity
No information avaliable
Romoxipride Patient Information
No information avaliable
Romoxipride Organisms Affected
Humans and other mammals
