PharmacyCodes



Remodulin en es it fr

Remodulin Brand names, Remodulin Analogs

Remodulin Brand Names Mixture

  • No information avaliable

Remodulin Chemical_Formula

C66H75Cl2N9O24

Remodulin RX_link

http://www.rxlist.com/cgi/generic2/vancomycin.htm

Remodulin fda sheet

Remodulin FDA

Remodulin msds (material safety sheet)

Remodulin MSDS

Remodulin Synthesis Reference

No information avaliable

Remodulin Molecular Weight

1449.25 g/mol

Remodulin Melting Point

No information avaliable

Remodulin H2O Solubility

No information avaliable

Remodulin State

Solid

Remodulin LogP

-0.47

Remodulin Dosage Forms

Capsules; Nonpyrogenic premixed 100 mL or 200 mL solution containing 500 mg or 1 g vancomycin for injection

Remodulin Indication

For the treatment of serious or severe infections caused by susceptible strains of methicillin-resistant (beta-lactam-resistant) staphylococci.

Remodulin Pharmacology

Vancomycin is a branched tricyclic glycosylated nonribosomal peptide produced by the fermentation of the Actinobacteria species Amycolatopsis orientalis (formerly Nocardia orientalis). It is often reserved as the "drug of last resort", used only after treatment with other antibiotics had failed. Vancomycin has been shown to be active against most strains of the following microorganisms, both in vitro and in clinical infections: Listeria monocytogenes, Streptococcus pyogenes, Streptococcus pneumoniae (including penicillin-resistant strains), Streptococcus agalactiae, Actinomyces species, and Lactobacillus species. The combination of vancomycin and an aminoglycoside acts synergistically in vitro against many strains of Staphylococcus aureus, Streptococcus bovis, enterococci, and the viridans group streptococci.

Remodulin Absorption

Poorly absorbed from gastrointestinal tract, however systemic absorption (up to 60%) may occur following intraperitoneal administration.

Remodulin side effects and Toxicity

The oral LD50 in mice is 5000 mg/kg. The median lethal intravenous dose is 319 mg/kg in rats and 400 mg/kg in mice.

Remodulin Patient Information

Remodulin Organisms Affected

Enteric bacteria and other eubacteria