Relaxazone
Brand names,
Relaxazone
Analogs
Relaxazone
Brand Names Mixture
- Acetazone Forte (Acetaminophen + Chlorzoxazone)
- Acetazone Forte C8 (Acetaminophen + Chlorzoxazone + Codeine Phosphate)
- Back-Aid Forte - Tab (Acetaminophen + Chlorzoxazone)
- Extra Strength Tylenol Aches and Strains (Acetaminophen + Chlorzoxazone)
- Gin Pain Pills - Tab (Acetaminophen + Chlorzoxazone)
- Gin Pain Pills- Chlorzoxazone & Acetamin.Tab (Acetaminophen + Chlorzoxazone)
- Parafon Forte (Acetaminophen + Chlorzoxazone)
- Parafon Forte C8 W Codeine Tab (Acetaminophen + Chlorzoxazone + Codeine Phosphate)
- Parafon Forte Tablets (Acetaminophen + Chlorzoxazone)
Relaxazone
Chemical_Formula
C7H4ClNO2
Relaxazone
RX_link
http://www.rxlist.com/cgi/generic2/chlorzox.htm
Relaxazone
fda sheet
Relaxazone
msds (material safety sheet)
Relaxazone
Synthesis Reference
No information avaliable
Relaxazone
Molecular Weight
169.565 g/mol
Relaxazone
Melting Point
191.5 oC
Relaxazone
H2O Solubility
1000 mg/L
Relaxazone
State
Solid
Relaxazone
LogP
1.659
Relaxazone
Dosage Forms
Tablet (500 mg)
Relaxazone
Indication
For the relief of discomfort associated with acute painful musculoskeletal conditions.
Relaxazone
Pharmacology
Chlorzoxazone, a synthetic compound, inhibits antigen-induced bronchospasms and, hence, is used to treat asthma and allergic rhinitis. Chlorzoxazone is used as an ophthalmic solution to treat conjunctivitis and is taken orally to treat systemic mastocytosis and ulcerative colitis. Chlorzoxazone is also a centrally-acting agent for painful musculoskeletal conditions. Data available from animal experiments as well as human study indicate that chlorzoxazone acts primarily at the level of the spinal cord and subcortical areas of the brain where it inhibits multisynaptic reflex a.c. involved in producing and maintaining skeletal muscle spasm of varied etiology. The clinical result is a reduction of the skeletal muscle spasm with relief of pain and increased mobility of the involved muscles.
Relaxazone
Absorption
No information avaliable
Relaxazone
side effects and Toxicity
Oral, mouse: LD50 = 440 mg/kg; Oral, rat: LD50 = 763 mg/kg; Symptoms of overdose include diarrhea, dizziness, drowsiness, headache, light-headedness, nausea, and vomiting.
Relaxazone
Patient Information
No information avaliable
Relaxazone
Organisms Affected
Humans and other mammals