Pathorysin
Brand names,
Pathorysin
Analogs
Pathorysin
Brand Names Mixture
- Acetazone Forte (Acetaminophen + Chlorzoxazone)
- Acetazone Forte C8 (Acetaminophen + Chlorzoxazone + Codeine Phosphate)
- Back-Aid Forte - Tab (Acetaminophen + Chlorzoxazone)
- Extra Strength Tylenol Aches and Strains (Acetaminophen + Chlorzoxazone)
- Gin Pain Pills - Tab (Acetaminophen + Chlorzoxazone)
- Gin Pain Pills- Chlorzoxazone & Acetamin.Tab (Acetaminophen + Chlorzoxazone)
- Parafon Forte (Acetaminophen + Chlorzoxazone)
- Parafon Forte C8 W Codeine Tab (Acetaminophen + Chlorzoxazone + Codeine Phosphate)
- Parafon Forte Tablets (Acetaminophen + Chlorzoxazone)
Pathorysin
Chemical_Formula
C7H4ClNO2
Pathorysin
RX_link
http://www.rxlist.com/cgi/generic2/chlorzox.htm
Pathorysin
fda sheet
Pathorysin
msds (material safety sheet)
Pathorysin
Synthesis Reference
No information avaliable
Pathorysin
Molecular Weight
169.565 g/mol
Pathorysin
Melting Point
191.5 oC
Pathorysin
H2O Solubility
1000 mg/L
Pathorysin
State
Solid
Pathorysin
LogP
1.659
Pathorysin
Dosage Forms
Tablet (500 mg)
Pathorysin
Indication
For the relief of discomfort associated with acute painful musculoskeletal conditions.
Pathorysin
Pharmacology
Chlorzoxazone, a synthetic compound, inhibits antigen-induced bronchospasms and, hence, is used to treat asthma and allergic rhinitis. Chlorzoxazone is used as an ophthalmic solution to treat conjunctivitis and is taken orally to treat systemic mastocytosis and ulcerative colitis. Chlorzoxazone is also a centrally-acting agent for painful musculoskeletal conditions. Data available from animal experiments as well as human study indicate that chlorzoxazone acts primarily at the level of the spinal cord and subcortical areas of the brain where it inhibits multisynaptic reflex a.c. involved in producing and maintaining skeletal muscle spasm of varied etiology. The clinical result is a reduction of the skeletal muscle spasm with relief of pain and increased mobility of the involved muscles.
Pathorysin
Absorption
No information avaliable
Pathorysin
side effects and Toxicity
Oral, mouse: LD50 = 440 mg/kg; Oral, rat: LD50 = 763 mg/kg; Symptoms of overdose include diarrhea, dizziness, drowsiness, headache, light-headedness, nausea, and vomiting.
Pathorysin
Patient Information
No information avaliable
Pathorysin
Organisms Affected
Humans and other mammals