Miotran
Brand names,
Miotran
Analogs
Miotran
Brand Names Mixture
- Acetazone Forte (Acetaminophen + Chlorzoxazone)
- Acetazone Forte C8 (Acetaminophen + Chlorzoxazone + Codeine Phosphate)
- Back-Aid Forte - Tab (Acetaminophen + Chlorzoxazone)
- Extra Strength Tylenol Aches and Strains (Acetaminophen + Chlorzoxazone)
- Gin Pain Pills - Tab (Acetaminophen + Chlorzoxazone)
- Gin Pain Pills- Chlorzoxazone & Acetamin.Tab (Acetaminophen + Chlorzoxazone)
- Parafon Forte (Acetaminophen + Chlorzoxazone)
- Parafon Forte C8 W Codeine Tab (Acetaminophen + Chlorzoxazone + Codeine Phosphate)
- Parafon Forte Tablets (Acetaminophen + Chlorzoxazone)
Miotran
Chemical_Formula
C7H4ClNO2
Miotran
RX_link
http://www.rxlist.com/cgi/generic2/chlorzox.htm
Miotran
fda sheet
Miotran
msds (material safety sheet)
Miotran
Synthesis Reference
No information avaliable
Miotran
Molecular Weight
169.565 g/mol
Miotran
Melting Point
191.5 oC
Miotran
H2O Solubility
1000 mg/L
Miotran
State
Solid
Miotran
LogP
1.659
Miotran
Dosage Forms
Tablet (500 mg)
Miotran
Indication
For the relief of discomfort associated with acute painful musculoskeletal conditions.
Miotran
Pharmacology
Chlorzoxazone, a synthetic compound, inhibits antigen-induced bronchospasms and, hence, is used to treat asthma and allergic rhinitis. Chlorzoxazone is used as an ophthalmic solution to treat conjunctivitis and is taken orally to treat systemic mastocytosis and ulcerative colitis. Chlorzoxazone is also a centrally-acting agent for painful musculoskeletal conditions. Data available from animal experiments as well as human study indicate that chlorzoxazone acts primarily at the level of the spinal cord and subcortical areas of the brain where it inhibits multisynaptic reflex a.c. involved in producing and maintaining skeletal muscle spasm of varied etiology. The clinical result is a reduction of the skeletal muscle spasm with relief of pain and increased mobility of the involved muscles.
Miotran
Absorption
No information avaliable
Miotran
side effects and Toxicity
Oral, mouse: LD50 = 440 mg/kg; Oral, rat: LD50 = 763 mg/kg; Symptoms of overdose include diarrhea, dizziness, drowsiness, headache, light-headedness, nausea, and vomiting.
Miotran
Patient Information
No information avaliable
Miotran
Organisms Affected
Humans and other mammals