Pyrazinamide
Pyrazinamide Brand names, Pyrazinamide Analogs
Pyrazinamide Brand Names Mixture
- No information avaliable
Pyrazinamide Chemical_Formula
C5H5N3O
Pyrazinamide RX_link
http://www.rxlist.com/cgi/generic2/pyrazinamide.htm
Pyrazinamide fda sheet
Pyrazinamide msds (material safety sheet)
Pyrazinamide Synthesis Reference
No information avaliable
Pyrazinamide Molecular Weight
123.113 g/mol
Pyrazinamide Melting Point
192 oC
Pyrazinamide H2O Solubility
1.5E+004 mg/L
Pyrazinamide State
Solid
Pyrazinamide LogP
-1.884
Pyrazinamide Dosage Forms
Tablet
Pyrazinamide Indication
For the initial treatment of active tuberculosis in adults and children when combined with other antituberculous agents.
Pyrazinamide Pharmacology
Pyrazinamide kills or stops the growth of certain bacteria that cause tuberculosis (TB). It is used with other drugs to treat tuberculosis. It is a highly specific agent and is active only against Mycobacterium tuberculosis. In vitro and in vivo, the drug is active only at a slightly acid pH.
Pyrazinamide Absorption
Rapidly and well absorbed from the gastrointestinal tract.
Pyrazinamide side effects and Toxicity
Side effects include liver injury, arthralgias, anorexia, nausea and vomiting, dysuria,malaise and fever, sideroblastic anemia, adverse effects on the blood clotting mechanism or vascular integrity, and hypersensitivity reactions such as urticaria, pruritis and skin rashes.
Pyrazinamide Patient Information
Pyrazinamide Organisms Affected
Mycobacterium tuberculosis
