Pralidoxime Chloride
Brand names,
Pralidoxime Chloride
Analogs
Pralidoxime Chloride
Brand Names Mixture
Pralidoxime Chloride
Chemical_Formula
C5H5N3O
Pralidoxime Chloride
RX_link
http://www.rxlist.com/cgi/generic2/pyrazinamide.htm
Pralidoxime Chloride
fda sheet
Pralidoxime Chloride
msds (material safety sheet)
Pralidoxime Chloride
Synthesis Reference
No information avaliable
Pralidoxime Chloride
Molecular Weight
123.113 g/mol
Pralidoxime Chloride
Melting Point
192 oC
Pralidoxime Chloride
H2O Solubility
1.5E+004 mg/L
Pralidoxime Chloride
State
Solid
Pralidoxime Chloride
LogP
-1.884
Pralidoxime Chloride
Dosage Forms
Tablet
Pralidoxime Chloride
Indication
For the initial treatment of active tuberculosis in adults and children when combined with other antituberculous agents.
Pralidoxime Chloride
Pharmacology
Pyrazinamide kills or stops the growth of certain bacteria that cause tuberculosis (TB). It is used with other drugs to treat tuberculosis. It is a highly specific agent and is active only against Mycobacterium tuberculosis. In vitro and in vivo, the drug is active only at a slightly acid pH.
Pralidoxime Chloride
Absorption
Rapidly and well absorbed from the gastrointestinal tract.
Pralidoxime Chloride
side effects and Toxicity
Side effects include liver injury, arthralgias, anorexia, nausea and vomiting, dysuria,malaise and fever, sideroblastic anemia, adverse effects on the blood clotting mechanism or vascular integrity, and hypersensitivity reactions such as urticaria, pruritis and skin rashes.
Pralidoxime Chloride
Patient Information
Pralidoxime Chloride
Organisms Affected
Mycobacterium tuberculosis