Protopam Chloride
Brand names,
Protopam Chloride
Analogs
Protopam Chloride
Brand Names Mixture
Protopam Chloride
Chemical_Formula
C5H5N3O
Protopam Chloride
RX_link
http://www.rxlist.com/cgi/generic2/pyrazinamide.htm
Protopam Chloride
fda sheet
Protopam Chloride
msds (material safety sheet)
Protopam Chloride
Synthesis Reference
No information avaliable
Protopam Chloride
Molecular Weight
123.113 g/mol
Protopam Chloride
Melting Point
192 oC
Protopam Chloride
H2O Solubility
1.5E+004 mg/L
Protopam Chloride
State
Solid
Protopam Chloride
LogP
-1.884
Protopam Chloride
Dosage Forms
Tablet
Protopam Chloride
Indication
For the initial treatment of active tuberculosis in adults and children when combined with other antituberculous agents.
Protopam Chloride
Pharmacology
Pyrazinamide kills or stops the growth of certain bacteria that cause tuberculosis (TB). It is used with other drugs to treat tuberculosis. It is a highly specific agent and is active only against Mycobacterium tuberculosis. In vitro and in vivo, the drug is active only at a slightly acid pH.
Protopam Chloride
Absorption
Rapidly and well absorbed from the gastrointestinal tract.
Protopam Chloride
side effects and Toxicity
Side effects include liver injury, arthralgias, anorexia, nausea and vomiting, dysuria,malaise and fever, sideroblastic anemia, adverse effects on the blood clotting mechanism or vascular integrity, and hypersensitivity reactions such as urticaria, pruritis and skin rashes.
Protopam Chloride
Patient Information
Protopam Chloride
Organisms Affected
Mycobacterium tuberculosis