Proguanil en es it fr

Proguanil Brand names, Proguanil Analogs

Proguanil Brand Names Mixture

  • No information avaliable

Proguanil Chemical_Formula


Proguanil RX_link

No information avaliable

Proguanil fda sheet

Proguanil msds (material safety sheet)

Proguanil Synthesis Reference

No information avaliable

Proguanil Molecular Weight

253.731 g/mol

Proguanil Melting Point

129 oC

Proguanil H2O Solubility

156 mg/L

Proguanil State


Proguanil LogP


Proguanil Dosage Forms


Proguanil Indication

For the causal prevention and suppression of malaria caused by susceptible strains of P. falciparum and other species of Plasmodium found in some geographical areas of the world.

Proguanil Pharmacology

Proguanil is a biguanide derivative that is converted to an active metabolite called cycloguanil pamoate. It exerts its antimalarial action by inhibiting parasitic dihydrofolate reductase enzyme. It has causal prophylactic and suppressive activity against P. falciparum and cures the acute infection. It is also effective in suppressing the clinical attacks of vivax malaria. However it is slower compared to 4-aminoquinolines.

Proguanil Absorption

Rapidly and well absorbed in humans following oral doses ranging from 50 to 500 mg.

Proguanil side effects and Toxicity

No information avaliable

Proguanil Patient Information

No information avaliable

Proguanil Organisms Affected