Chloroguanide en es it fr

Chloroguanide Brand names, Chloroguanide Analogs

Chloroguanide Brand Names Mixture

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Chloroguanide Chemical_Formula


Chloroguanide RX_link

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Chloroguanide fda sheet

Chloroguanide msds (material safety sheet)

Chloroguanide Synthesis Reference

No information avaliable

Chloroguanide Molecular Weight

253.731 g/mol

Chloroguanide Melting Point

129 oC

Chloroguanide H2O Solubility

156 mg/L

Chloroguanide State


Chloroguanide LogP


Chloroguanide Dosage Forms


Chloroguanide Indication

For the causal prevention and suppression of malaria caused by susceptible strains of P. falciparum and other species of Plasmodium found in some geographical areas of the world.

Chloroguanide Pharmacology

Proguanil is a biguanide derivative that is converted to an active metabolite called cycloguanil pamoate. It exerts its antimalarial action by inhibiting parasitic dihydrofolate reductase enzyme. It has causal prophylactic and suppressive activity against P. falciparum and cures the acute infection. It is also effective in suppressing the clinical attacks of vivax malaria. However it is slower compared to 4-aminoquinolines.

Chloroguanide Absorption

Rapidly and well absorbed in humans following oral doses ranging from 50 to 500 mg.

Chloroguanide side effects and Toxicity

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Chloroguanide Patient Information

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Chloroguanide Organisms Affected