Plenaxis (Praecis Pharmaceuticals)
Brand names,
Plenaxis (Praecis Pharmaceuticals)
Analogs
Plenaxis (Praecis Pharmaceuticals)
Brand Names Mixture
Plenaxis (Praecis Pharmaceuticals)
Chemical_Formula
C72H95O14N14Cl
Plenaxis (Praecis Pharmaceuticals)
RX_link
http://www.rxlist.com/cgi/generic3/plenaxis.htm
Plenaxis (Praecis Pharmaceuticals)
fda sheet
Plenaxis (Praecis Pharmaceuticals)
msds (material safety sheet)
Plenaxis (Praecis Pharmaceuticals)
Synthesis Reference
No information avaliable
Plenaxis (Praecis Pharmaceuticals)
Molecular Weight
1416.06
Plenaxis (Praecis Pharmaceuticals)
Melting Point
No information avaliable
Plenaxis (Praecis Pharmaceuticals)
H2O Solubility
No information avaliable
Plenaxis (Praecis Pharmaceuticals)
State
Liquid
Plenaxis (Praecis Pharmaceuticals)
LogP
No information avaliable
Plenaxis (Praecis Pharmaceuticals)
Dosage Forms
Suspension (IM Injection)
Plenaxis (Praecis Pharmaceuticals)
Indication
For palliative treatment of advanced prostate cancer.
Plenaxis (Praecis Pharmaceuticals)
Pharmacology
Used in the palliative treatment of advanced prostate cancer. Abarelix is a luteinizing hormone agonist that results in suppression of testicular or follicular steroidogenesis.
Plenaxis (Praecis Pharmaceuticals)
Absorption
Following IM administration of 100 mg, abarelix is absorbed slowly with a mean peak concentration of 43.4 ng/mL observed approximately 3 days after the injection.
Plenaxis (Praecis Pharmaceuticals)
side effects and Toxicity
The maximum tolerated dose of abarelix has not been determined. The maximum dose used in clinical studies was 150 mg. There have been no reports of accidental overdose with abarelix.
Plenaxis (Praecis Pharmaceuticals)
Patient Information
No information avaliable
Plenaxis (Praecis Pharmaceuticals)
Organisms Affected
Humans and other mammals