Plenaxis
Brand names,
Plenaxis
Analogs
Plenaxis
Brand Names Mixture
Plenaxis
Chemical_Formula
C72H95O14N14Cl
Plenaxis
RX_link
http://www.rxlist.com/cgi/generic3/plenaxis.htm
Plenaxis
fda sheet
Plenaxis
msds (material safety sheet)
Plenaxis
Synthesis Reference
No information avaliable
Plenaxis
Molecular Weight
1416.06
Plenaxis
Melting Point
No information avaliable
Plenaxis
H2O Solubility
No information avaliable
Plenaxis
State
Liquid
Plenaxis
LogP
No information avaliable
Plenaxis
Dosage Forms
Suspension (IM Injection)
Plenaxis
Indication
For palliative treatment of advanced prostate cancer.
Plenaxis
Pharmacology
Used in the palliative treatment of advanced prostate cancer. Abarelix is a luteinizing hormone agonist that results in suppression of testicular or follicular steroidogenesis.
Plenaxis
Absorption
Following IM administration of 100 mg, abarelix is absorbed slowly with a mean peak concentration of 43.4 ng/mL observed approximately 3 days after the injection.
Plenaxis
side effects and Toxicity
The maximum tolerated dose of abarelix has not been determined. The maximum dose used in clinical studies was 150 mg. There have been no reports of accidental overdose with abarelix.
Plenaxis
Patient Information
No information avaliable
Plenaxis
Organisms Affected
Humans and other mammals