Piperazine hydrate
Brand names,
Piperazine hydrate
Analogs
Piperazine hydrate
Brand Names Mixture
- Canoids Cap (Aloin + Areca Catechu + Arecoline HBr + Benzocaine + Piperazine Citrate + Santonin)
- Dyrex T F (Phenothiazine + Piperazine + Trichlorfon)
- Feloids Tab (Aloin + Areca Catechu + Arecoline HBr + Benzocaine + Piperazine Citrate + Santonin)
- Multi Wormer for Cats (Dichlorophene + Piperazine (Piperazine Citrate))
- Multi Wormer for Dogs (Dichlorophene + Piperazine (Piperazine Citrate))
- Ripercol Horse Wormer (Piperazine (Piperazine Hydrochloride) + Tetramisole HCl)
Piperazine hydrate
Chemical_Formula
C4H10N2
Piperazine hydrate
RX_link
No information avaliable
Piperazine hydrate
fda sheet
Piperazine hydrate
msds (material safety sheet)
Piperazine hydrate
Synthesis Reference
No information avaliable
Piperazine hydrate
Molecular Weight
86.1357 g/mol
Piperazine hydrate
Melting Point
106 oC
Piperazine hydrate
H2O Solubility
150 mg/mL
Piperazine hydrate
State
Solid
Piperazine hydrate
LogP
-0.836
Piperazine hydrate
Dosage Forms
Capsule; Drops; Liquid; Powder; Powder for solution; Solution; Suspension; Syrup; Tablet
Piperazine hydrate
Indication
Used as alternative treatment for ascariasis caused by Ascaris lumbricoides (roundworm) and enterobiasis (oxyuriasis) caused by Enterobius vermicularis (pinworm). It is also used to treat partial intestinal obstruction by the common roundworm, a condition primarily occurring in children.
Piperazine hydrate
Pharmacology
Piperazine is an anthelminthic especially useful in the treatment of partial intestinal obstruction caused by Ascaris worms, which is a condition primarily seen in children. Piperazine hydrate and piperazine citrate are the main anthelminthic piperazines.
Piperazine hydrate
Absorption
Rapidly absorbed from the gastrointestinal tract
Piperazine hydrate
side effects and Toxicity
LD50 = 5 g/kg (Human, oral). Symptoms of overdose include muscle fatigue, seizures, and difficulty breathing.
Piperazine hydrate
Patient Information
No information avaliable
Piperazine hydrate
Organisms Affected
Parasitic nematodes and other roundworms