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Brand names,
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Analogs
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Brand Names Mixture
- Canoids Cap (Aloin + Areca Catechu + Arecoline HBr + Benzocaine + Piperazine Citrate + Santonin)
- Dyrex T F (Phenothiazine + Piperazine + Trichlorfon)
- Feloids Tab (Aloin + Areca Catechu + Arecoline HBr + Benzocaine + Piperazine Citrate + Santonin)
- Multi Wormer for Cats (Dichlorophene + Piperazine (Piperazine Citrate))
- Multi Wormer for Dogs (Dichlorophene + Piperazine (Piperazine Citrate))
- Ripercol Horse Wormer (Piperazine (Piperazine Hydrochloride) + Tetramisole HCl)
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Chemical_Formula
C4H10N2
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RX_link
No information avaliable
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
86.1357 g/mol
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Melting Point
106 oC
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H2O Solubility
150 mg/mL
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State
Solid
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LogP
-0.836
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Dosage Forms
Capsule; Drops; Liquid; Powder; Powder for solution; Solution; Suspension; Syrup; Tablet
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Indication
Used as alternative treatment for ascariasis caused by Ascaris lumbricoides (roundworm) and enterobiasis (oxyuriasis) caused by Enterobius vermicularis (pinworm). It is also used to treat partial intestinal obstruction by the common roundworm, a condition primarily occurring in children.
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Pharmacology
Piperazine is an anthelminthic especially useful in the treatment of partial intestinal obstruction caused by Ascaris worms, which is a condition primarily seen in children. Piperazine hydrate and piperazine citrate are the main anthelminthic piperazines.
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Absorption
Rapidly absorbed from the gastrointestinal tract
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side effects and Toxicity
LD50 = 5 g/kg (Human, oral). Symptoms of overdose include muscle fatigue, seizures, and difficulty breathing.
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Patient Information
No information avaliable
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Organisms Affected
Parasitic nematodes and other roundworms