Diketopiperazine
Brand names,
Diketopiperazine
Analogs
Diketopiperazine
Brand Names Mixture
- Canoids Cap (Aloin + Areca Catechu + Arecoline HBr + Benzocaine + Piperazine Citrate + Santonin)
- Dyrex T F (Phenothiazine + Piperazine + Trichlorfon)
- Feloids Tab (Aloin + Areca Catechu + Arecoline HBr + Benzocaine + Piperazine Citrate + Santonin)
- Multi Wormer for Cats (Dichlorophene + Piperazine (Piperazine Citrate))
- Multi Wormer for Dogs (Dichlorophene + Piperazine (Piperazine Citrate))
- Ripercol Horse Wormer (Piperazine (Piperazine Hydrochloride) + Tetramisole HCl)
Diketopiperazine
Chemical_Formula
C4H10N2
Diketopiperazine
RX_link
No information avaliable
Diketopiperazine
fda sheet
Diketopiperazine
msds (material safety sheet)
Diketopiperazine
Synthesis Reference
No information avaliable
Diketopiperazine
Molecular Weight
86.1357 g/mol
Diketopiperazine
Melting Point
106 oC
Diketopiperazine
H2O Solubility
150 mg/mL
Diketopiperazine
State
Solid
Diketopiperazine
LogP
-0.836
Diketopiperazine
Dosage Forms
Capsule; Drops; Liquid; Powder; Powder for solution; Solution; Suspension; Syrup; Tablet
Diketopiperazine
Indication
Used as alternative treatment for ascariasis caused by Ascaris lumbricoides (roundworm) and enterobiasis (oxyuriasis) caused by Enterobius vermicularis (pinworm). It is also used to treat partial intestinal obstruction by the common roundworm, a condition primarily occurring in children.
Diketopiperazine
Pharmacology
Piperazine is an anthelminthic especially useful in the treatment of partial intestinal obstruction caused by Ascaris worms, which is a condition primarily seen in children. Piperazine hydrate and piperazine citrate are the main anthelminthic piperazines.
Diketopiperazine
Absorption
Rapidly absorbed from the gastrointestinal tract
Diketopiperazine
side effects and Toxicity
LD50 = 5 g/kg (Human, oral). Symptoms of overdose include muscle fatigue, seizures, and difficulty breathing.
Diketopiperazine
Patient Information
No information avaliable
Diketopiperazine
Organisms Affected
Parasitic nematodes and other roundworms