Perindopril
Perindopril Brand names, Perindopril Analogs
Perindopril Brand Names Mixture
- No information avaliable
Perindopril Chemical_Formula
C7H9N2O+
Perindopril RX_link
http://www.rxlist.com/cgi/generic2/pralidoxime.htm
Perindopril fda sheet
Perindopril msds (material safety sheet)
Perindopril Synthesis Reference
No information avaliable
Perindopril Molecular Weight
137.159 g/mol
Perindopril Melting Point
215-225 oC
Perindopril H2O Solubility
No information avaliable
Perindopril State
Solid
Perindopril LogP
1.564
Perindopril Dosage Forms
Powder for solution
Perindopril Indication
For the treatment of poisoning due to those pesticides and chemicals of the organophosphate class which have anticholinesterase activity and in the control of overdosage by anticholinesterase drugs used in the treatment of myasthenia gravis.
Perindopril Pharmacology
Pralidoxime is to reactivate cholinesterase (mainly outside of the central nervous system) which has been inactivated by phosphorylation due to an organophosphate pesticide or related compound. The destruction of accumulated acetylcholine can then proceed, and neuromuscular junctions will again function normally. Pralidoxime also slows the process of "aging" of phosphorylated cholinesterase to a nonreactivatable form, and detoxifies certain organophosphates by direct chemical reaction. The drug has its most critical effect in relieving paralysis of the muscles of respiration. Because pralidoxime is less effective in relieving depression of the respiratory center, atropine is always required concomitantly to block the effect of accumulated acetylcholine at this site. Pralidoxime relieves muscarinic signs and symptoms, salivation, bronchospasm, etc., but this action is relatively unimportant since atropine is adequate for this purpose.
Perindopril Absorption
No information avaliable
Perindopril side effects and Toxicity
No information avaliable
Perindopril Patient Information
No information avaliable
Perindopril Organisms Affected
Humans and other mammals
