Aceon
Aceon Brand names, Aceon Analogs
Aceon Brand Names Mixture
- No information avaliable
Aceon Chemical_Formula
C7H9N2O+
Aceon RX_link
http://www.rxlist.com/cgi/generic2/pralidoxime.htm
Aceon fda sheet
Aceon msds (material safety sheet)
Aceon Synthesis Reference
No information avaliable
Aceon Molecular Weight
137.159 g/mol
Aceon Melting Point
215-225 oC
Aceon H2O Solubility
No information avaliable
Aceon State
Solid
Aceon LogP
1.564
Aceon Dosage Forms
Powder for solution
Aceon Indication
For the treatment of poisoning due to those pesticides and chemicals of the organophosphate class which have anticholinesterase activity and in the control of overdosage by anticholinesterase drugs used in the treatment of myasthenia gravis.
Aceon Pharmacology
Pralidoxime is to reactivate cholinesterase (mainly outside of the central nervous system) which has been inactivated by phosphorylation due to an organophosphate pesticide or related compound. The destruction of accumulated acetylcholine can then proceed, and neuromuscular junctions will again function normally. Pralidoxime also slows the process of "aging" of phosphorylated cholinesterase to a nonreactivatable form, and detoxifies certain organophosphates by direct chemical reaction. The drug has its most critical effect in relieving paralysis of the muscles of respiration. Because pralidoxime is less effective in relieving depression of the respiratory center, atropine is always required concomitantly to block the effect of accumulated acetylcholine at this site. Pralidoxime relieves muscarinic signs and symptoms, salivation, bronchospasm, etc., but this action is relatively unimportant since atropine is adequate for this purpose.
Aceon Absorption
No information avaliable
Aceon side effects and Toxicity
No information avaliable
Aceon Patient Information
No information avaliable
Aceon Organisms Affected
Humans and other mammals
