Pemetrexed Disodium
Brand names,
Pemetrexed Disodium
Analogs
Pemetrexed Disodium
Brand Names Mixture
Pemetrexed Disodium
Chemical_Formula
C20H21N5O6
Pemetrexed Disodium
RX_link
http://www.rxlist.com/cgi/generic3/alimta.htm
Pemetrexed Disodium
fda sheet
Pemetrexed Disodium
msds (material safety sheet)
Pemetrexed Disodium
Synthesis Reference
No information avaliable
Pemetrexed Disodium
Molecular Weight
427.411 g/mol
Pemetrexed Disodium
Melting Point
No information avaliable
Pemetrexed Disodium
H2O Solubility
No information avaliable
Pemetrexed Disodium
State
Solid
Pemetrexed Disodium
LogP
No information avaliable
Pemetrexed Disodium
Dosage Forms
Powder for solution; Intravenous infusion
Pemetrexed Disodium
Indication
For the treatment of malignant pleural mesothelioma and locally advanced or metastatic non-small cell lung cancer (NSCLC) after prior chemotherapy
Pemetrexed Disodium
Pharmacology
Preclinical studies have shown that pemetrexed inhibits the in vitro growth of mesothelioma cell lines (MSTO-211H, NCI-H2052). Studies with the MSTO-211H mesothelioma cell line showed synergistic effects when pemetrexed was combined concurrently with cisplatin.
Pemetrexed Disodium
Absorption
No information avaliable
Pemetrexed Disodium
side effects and Toxicity
No information avaliable
Pemetrexed Disodium
Patient Information
Pemetrexed Disodium
Organisms Affected
Humans and other mammals