Pemetrexed
Brand names,
Pemetrexed
Analogs
Pemetrexed
Brand Names Mixture
Pemetrexed
Chemical_Formula
C20H21N5O6
Pemetrexed
RX_link
http://www.rxlist.com/cgi/generic3/alimta.htm
Pemetrexed
fda sheet
Pemetrexed
msds (material safety sheet)
Pemetrexed
Synthesis Reference
No information avaliable
Pemetrexed
Molecular Weight
427.411 g/mol
Pemetrexed
Melting Point
No information avaliable
Pemetrexed
H2O Solubility
No information avaliable
Pemetrexed
State
Solid
Pemetrexed
LogP
No information avaliable
Pemetrexed
Dosage Forms
Powder for solution; Intravenous infusion
Pemetrexed
Indication
For the treatment of malignant pleural mesothelioma and locally advanced or metastatic non-small cell lung cancer (NSCLC) after prior chemotherapy
Pemetrexed
Pharmacology
Preclinical studies have shown that pemetrexed inhibits the in vitro growth of mesothelioma cell lines (MSTO-211H, NCI-H2052). Studies with the MSTO-211H mesothelioma cell line showed synergistic effects when pemetrexed was combined concurrently with cisplatin.
Pemetrexed
Absorption
No information avaliable
Pemetrexed
side effects and Toxicity
No information avaliable
Pemetrexed
Patient Information
Pemetrexed
Organisms Affected
Humans and other mammals