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Parametadione [DCIT] en es it fr

Parametadione [DCIT] Brand names, Parametadione [DCIT] Analogs

Parametadione [DCIT] Brand Names Mixture

  • No information avaliable

Parametadione [DCIT] Chemical_Formula

C7H11NO3

Parametadione [DCIT] RX_link

No information avaliable

Parametadione [DCIT] fda sheet

Parametadione [DCIT] msds (material safety sheet)

Parametadione [DCIT] Synthesis Reference

No information avaliable

Parametadione [DCIT] Molecular Weight

157.167 g/mol

Parametadione [DCIT] Melting Point

101.5 oC (boiling point)

Parametadione [DCIT] H2O Solubility

8.4 mg/mL

Parametadione [DCIT] State

Liquid

Parametadione [DCIT] LogP

0.763

Parametadione [DCIT] Dosage Forms

Tablet

Parametadione [DCIT] Indication

Used for the control of absence (petit mal) seizures that are refractory to treatment with other medications.

Parametadione [DCIT] Pharmacology

Paramethadione is an oxazolidinedione anticonvulsant similar to trimethadione that acts on the central nervous system (CNS) to reduce the number of absence seizures (often seen in epileptics). Absence seizures involve an interruption to consciousness where the person experiencing the seizure seems to become vacant and unresponsive for a short period of time (usually up to 30 seconds). Paramethadione acts on thalamic neurons in the thalamic reticular nucleus (which studies have shown to be associated with absence seizures, von Krosigk et al., 1993).

Parametadione [DCIT] Absorption

Rapid via the digestive tract.

Parametadione [DCIT] side effects and Toxicity

Symptoms of overdose include clumsiness or unsteadiness, coma, severe dizziness, severe drowsiness, severe nausea, and problems with vision.

Parametadione [DCIT] Patient Information

Dione anticonvulsants are used to control certain types of seizures in the treatment of epilepsy. They act on the central nervous system (CNS) to reduce the number of seizures. These medicines cannot cure epilepsy and will only work to control seizures for as long as you continue to take them.

Parametadione [DCIT] Organisms Affected

Humans and other mammals