Parametadione
Parametadione Brand names, Parametadione Analogs
Parametadione Brand Names Mixture
- No information avaliable
Parametadione Chemical_Formula
C7H11NO3
Parametadione RX_link
No information avaliable
Parametadione fda sheet
Parametadione msds (material safety sheet)
Parametadione Synthesis Reference
No information avaliable
Parametadione Molecular Weight
157.167 g/mol
Parametadione Melting Point
101.5 oC (boiling point)
Parametadione H2O Solubility
8.4 mg/mL
Parametadione State
Liquid
Parametadione LogP
0.763
Parametadione Dosage Forms
Tablet
Parametadione Indication
Used for the control of absence (petit mal) seizures that are refractory to treatment with other medications.
Parametadione Pharmacology
Paramethadione is an oxazolidinedione anticonvulsant similar to trimethadione that acts on the central nervous system (CNS) to reduce the number of absence seizures (often seen in epileptics). Absence seizures involve an interruption to consciousness where the person experiencing the seizure seems to become vacant and unresponsive for a short period of time (usually up to 30 seconds). Paramethadione acts on thalamic neurons in the thalamic reticular nucleus (which studies have shown to be associated with absence seizures, von Krosigk et al., 1993).
Parametadione Absorption
Rapid via the digestive tract.
Parametadione side effects and Toxicity
Symptoms of overdose include clumsiness or unsteadiness, coma, severe dizziness, severe drowsiness, severe nausea, and problems with vision.
Parametadione Patient Information
Dione anticonvulsants are used to control certain types of seizures in the treatment of epilepsy. They act on the central nervous system (CNS) to reduce the number of seizures. These medicines cannot cure epilepsy and will only work to control seizures for as long as you continue to take them.
Parametadione Organisms Affected
Humans and other mammals
