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Isoethadione Brand names, Isoethadione Analogs

Isoethadione Brand Names Mixture

  • No information avaliable

Isoethadione Chemical_Formula


Isoethadione RX_link

No information avaliable

Isoethadione fda sheet

Isoethadione msds (material safety sheet)

Isoethadione Synthesis Reference

No information avaliable

Isoethadione Molecular Weight

157.167 g/mol

Isoethadione Melting Point

101.5 oC (boiling point)

Isoethadione H2O Solubility

8.4 mg/mL

Isoethadione State


Isoethadione LogP


Isoethadione Dosage Forms


Isoethadione Indication

Used for the control of absence (petit mal) seizures that are refractory to treatment with other medications.

Isoethadione Pharmacology

Paramethadione is an oxazolidinedione anticonvulsant similar to trimethadione that acts on the central nervous system (CNS) to reduce the number of absence seizures (often seen in epileptics). Absence seizures involve an interruption to consciousness where the person experiencing the seizure seems to become vacant and unresponsive for a short period of time (usually up to 30 seconds). Paramethadione acts on thalamic neurons in the thalamic reticular nucleus (which studies have shown to be associated with absence seizures, von Krosigk et al., 1993).

Isoethadione Absorption

Rapid via the digestive tract.

Isoethadione side effects and Toxicity

Symptoms of overdose include clumsiness or unsteadiness, coma, severe dizziness, severe drowsiness, severe nausea, and problems with vision.

Isoethadione Patient Information

Dione anticonvulsants are used to control certain types of seizures in the treatment of epilepsy. They act on the central nervous system (CNS) to reduce the number of seizures. These medicines cannot cure epilepsy and will only work to control seizures for as long as you continue to take them.

Isoethadione Organisms Affected

Humans and other mammals