Paracortol

Paracortol Brand names, Paracortol Analogs

Paracortol Brand Names Mixture

Ak Cide Oph Soln (Prednisolone Acetate + Sulfacetamide Sodium)
Blephamide Oph Ont (Prednisolone Acetate + Sulfacetamide Sodium)
Blephamide Opht Suspension (Prednisolone Acetate + Sulfacetamide Sodium)
Canaural (Ear Drops) (Diethanolamine Fusidate + Framycetin Sulfate + Nystatin + Prednisolone)
Chlorasone (Chloramphenicol + Prednisolone Acetate)
Delta-Albaplex Tablets (Novobiocin (Novobiocin Sodium) + Prednisolone + Tetracycline Hydrochloride)
Dioptimyd Ointment (Prednisolone Acetate + Sulfacetamide Sodium)
Dioptimyd Suspension (Prednisolone Acetate + Sulfacetamide Sodium)
Liquichlor (Chloramphenicol + Prednisolone + Squalane + Tetracaine)
Metimyd Oph Sus (Prednisolone Acetate + Sulfacetamide Sodium)
Optisone (Neomycin + Prednisolone)
Pred C Tab (Aluminum Hydroxide + Prednisolone + Salicylamide + Vitamin C)
Prednisize Solution (Camphor + Chlorophenol + Cresyl Acetate + Prednisolone)
Quiex-Pred Sus (Aminophylline + Guaifenesin + Prednisolone)
Surolan Drops (Miconazole Nitrate + Polymyxin B Sulfate + Prednisolone Acetate)
Vanectyl-P Tablets (Prednisolone + Trimeprazine Tartrate)
Vasocidin Ophthalmic Solution (Prednisolone Sodium Phosphate + Sulfacetamide Sodium)

Paracortol Chemical_Formula

C₂₁H₂₈O₅

Paracortol RX_link

http://www.rxlist.com/cgi/generic/prednisolone.htm

Paracortol fda sheet

Paracortol FDA

Paracortol msds (material safety sheet)

Paracortol MSDS

Paracortol Synthesis Reference

No information avaliable

Paracortol Molecular Weight

360.444 g/mol

Paracortol Melting Point

235 ^oC

Paracortol H₂O Solubility

223 mg/L

Paracortol State

Solid

Paracortol LogP

1.705

Paracortol Dosage Forms

Solution

Paracortol Indication

For the treatment of primary or secondary adrenocortical insufficiency, such as congenital adrenal hyperplasia, thyroiditis. Also used to treat psoriatic arthritis, rheumatoid arthritis, ankylosing spondylitis, bursitis, acute gouty arthritis and epicondylitis. Also indicated for treatment of systemic lupus erythematosus, pemphigus and acute rhematic carditis. Can be used in the treatment of leukemias, lymphomas, thrombocytopenia purpura and autoimmune hemolytic anemia. Can be used to treat celiac disease, insulin resistance, ulcerative colitis and liver disorders.

Paracortol Pharmacology

Prednisolone is a synthetic glucocorticoid used as antiinflammatory or immunosuppressive agent. Prednisolone is indicated in the treatment of various conditions, including congenital adrenal hyperplasia, psoriatic arthritis, systemic lupus erythematosus, bullous dermatitis herpetiformis, seasonal or perennial allergic rhinitis, allergic corneal marginal ulcers, symptomatic sarcoidosis, idiopathic thrombocytopenic purpura in adults, leukemias and lymphomas in adults, and ulcerative colitis. Glucocorticoids are adrenocortical steroids and cause profound and varied metabolic effects. In addition, they modify the body's immune responses to diverse stimuli.

Paracortol Absorption

Readily absorbed by gastrointestinal tract, peak plasma concentration is reached 1-2 hours after administration.

Paracortol side effects and Toxicity

LD₅₀=500 mg/kg (oral, rat), short-term side effects include high blood glucose levels and fluid retention. Long term side effects include Cushing's syndrome, weight gain, osteoporosis, glaucoma, type II diabetes and adrenal suppression.

Paracortol Patient Information

Patients who are on immunosuppressant doses of corticosteroids should be warned to avoid exposure to chickenpox or measles. Patients should also be advised that if they are exposed, medical advice should be sought without delay.

Paracortol Organisms Affected

Humans and other mammals