P-Aminobenzoic Acid, Ethyl Ester
Brand names,
P-Aminobenzoic Acid, Ethyl Ester
Analogs
P-Aminobenzoic Acid, Ethyl Ester
Brand Names Mixture
P-Aminobenzoic Acid, Ethyl Ester
Chemical_Formula
C9H11NO2
P-Aminobenzoic Acid, Ethyl Ester
RX_link
http://www.rxlist.com/cgi/generic3/americaine.htm
P-Aminobenzoic Acid, Ethyl Ester
fda sheet
P-Aminobenzoic Acid, Ethyl Ester
msds (material safety sheet)
P-Aminobenzoic Acid, Ethyl Ester
Synthesis Reference
No information avaliable
P-Aminobenzoic Acid, Ethyl Ester
Molecular Weight
165.189 g/mol
P-Aminobenzoic Acid, Ethyl Ester
Melting Point
92 oC
P-Aminobenzoic Acid, Ethyl Ester
H2O Solubility
1310 mg/L
P-Aminobenzoic Acid, Ethyl Ester
State
Solid
P-Aminobenzoic Acid, Ethyl Ester
LogP
1.536
P-Aminobenzoic Acid, Ethyl Ester
Dosage Forms
Dental paste; Film-forming gel; Liquid; Ointment
P-Aminobenzoic Acid, Ethyl Ester
Indication
For general use as a lubricant and topical anesthetic on esophagus, larynx, mouth, nasal cavity, rectum, respiratory tract or trachea, urinary tract, vagina. It is also used to suppress gag reflex.
P-Aminobenzoic Acid, Ethyl Ester
Pharmacology
Benzocaine is a local anesthetic commonly used as a topical pain reliever. It is the active ingredient in many over-the-counter analgesic ointments. It is also indicated for general use as a lubricant and topical anesthetic on intratracheal catheters and pharyngeal and nasal airways to obtund the pharyngeal and tracheal reflexes; on nasogastric and endoscopic tubes; urinary catheters; laryngoscopes; proctoscopes; sigmoidoscopes and vaginal specula.
P-Aminobenzoic Acid, Ethyl Ester
Absorption
No information avaliable
P-Aminobenzoic Acid, Ethyl Ester
side effects and Toxicity
LD50=3040 mg/kg (rat, oral)
P-Aminobenzoic Acid, Ethyl Ester
Patient Information
P-Aminobenzoic Acid, Ethyl Ester
Organisms Affected
Humans and other mammals