Oxcarbamazepine
Oxcarbamazepine Brand names, Oxcarbamazepine Analogs
Oxcarbamazepine Brand Names Mixture
- No information avaliable
Oxcarbamazepine Chemical_Formula
C10H16N2O8
Oxcarbamazepine RX_link
http://www.rxlist.com/cgi/generic2/canaversenate.htm
Oxcarbamazepine fda sheet
Oxcarbamazepine msds (material safety sheet)
Oxcarbamazepine Synthesis Reference
No information avaliable
Oxcarbamazepine Molecular Weight
292.243 g/mol
Oxcarbamazepine Melting Point
No information avaliable
Oxcarbamazepine H2O Solubility
1000000 mg/L at 25 oC [MEYLAN,WM et al. (1996)]
Oxcarbamazepine State
No information avaliable
Oxcarbamazepine LogP
-2.238
Oxcarbamazepine Dosage Forms
Solution (for intravenous infusion or intramuscular injection)
Oxcarbamazepine Indication
For the reduction of blood levels and depot stores of lead in lead poisoning (acute and chronic) and lead encephalopathy, in both pediatric populations and adults.
Oxcarbamazepine Pharmacology
Edetate Calcium is a heavy metal chelating agent. The calcium in edetate calcium can be displaced by divalent or trivalent metals to form a stable water soluble complex that can be excreted in the urine. In theory, 1 g of edetate calcium can theoretically bind 620 mg of lead, but in reality only about 5 mg per gram is actually excreted into the urine in lead poisoned patients. In addition to chelating lead, edetate calcium also chelates and eliminates zinc from the body. Edetate calcium also binds cadmium, copper, iron and manganese, but to a much lesser extent than either lead or zinc. Edetate calcium is relatively ineffective for use in treating mercury, gold or arsenic poisoning.
Oxcarbamazepine Absorption
Poorly absorbed from the gastrointestinal tract. Well absorbed following intramuscular injection.
Oxcarbamazepine side effects and Toxicity
Inadvertent administration of 5 times the recommended dose, infused intravenously over a 24 hour period, to an asymptomatic 16 month old patient with a blood lead content of 56 mcg/dl did not cause any ill effects. Edetate calcium disodium can aggravate the symptoms of severe lead poisoning, therefore, most toxic effects (cerebral edema, renal tubular necrosis) appear to be associated with lead poisoning. Because of cerebral edema, a therapeutic dose may be lethal to an adult or a pediatric patient with lead encephalopathy. Higher dosage of edetate calcium disodium may produce a more severe zinc deficiency.
Oxcarbamazepine Patient Information
No information avaliable
Oxcarbamazepine Organisms Affected
Humans and other mammals
