Omapatrilat
Omapatrilat Brand names, Omapatrilat Analogs
Omapatrilat Brand Names Mixture
- No information avaliable
Omapatrilat Chemical_Formula
C19H24N2O4S2
Omapatrilat RX_link
No information avaliable
Omapatrilat fda sheet
Omapatrilat msds (material safety sheet)
Omapatrilat Synthesis Reference
No information avaliable
Omapatrilat Molecular Weight
408.537 g/mol
Omapatrilat Melting Point
No information avaliable
Omapatrilat H2O Solubility
No information avaliable
Omapatrilat State
Solid
Omapatrilat LogP
2.541
Omapatrilat Dosage Forms
No information avaliable
Omapatrilat Indication
For the treatment of hypertension
Omapatrilat Pharmacology
Omapatrilat is used to treat hypertension. Vasopeptidase inhibitor that simultaneously inhibits angiotensin-converting enzyme (ACE) and neutral endopeptidase (NEP). Omapatrilat lowers blood pressure by inhibiting the action of the angiotensin converting enzyme (ACE), which causes blood vessels to constrict. But unlike other drugs, omapatrilat also inhibits another enzyme known as neutral endopeptidase (NEP), which helps blood vessels relax. Omapatrilat demonstrated greater reduction in blood pressure than the ACE inhibitor lisinopril in individuals with salt-sensitive hypertension who typically do not respond well to ACE inhibitors.
Omapatrilat Absorption
The absolute oral bioavailability of omapatrilat is 20% to 30% and the absorption is not affected by food intake.
Omapatrilat side effects and Toxicity
Side effects include hyperkalemia, cough, hypotension, increased SrCr, and dizziness. Dizziness, diarrhea, vision disturbance, hypotension and angioedema
Omapatrilat Patient Information
No information avaliable
Omapatrilat Organisms Affected
Humans and other mammals
