Vanlev
Vanlev Brand names, Vanlev Analogs
Vanlev Brand Names Mixture
- No information avaliable
Vanlev Chemical_Formula
C19H24N2O4S2
Vanlev RX_link
No information avaliable
Vanlev fda sheet
Vanlev msds (material safety sheet)
Vanlev Synthesis Reference
No information avaliable
Vanlev Molecular Weight
408.537 g/mol
Vanlev Melting Point
No information avaliable
Vanlev H2O Solubility
No information avaliable
Vanlev State
Solid
Vanlev LogP
2.541
Vanlev Dosage Forms
No information avaliable
Vanlev Indication
For the treatment of hypertension
Vanlev Pharmacology
Omapatrilat is used to treat hypertension. Vasopeptidase inhibitor that simultaneously inhibits angiotensin-converting enzyme (ACE) and neutral endopeptidase (NEP). Omapatrilat lowers blood pressure by inhibiting the action of the angiotensin converting enzyme (ACE), which causes blood vessels to constrict. But unlike other drugs, omapatrilat also inhibits another enzyme known as neutral endopeptidase (NEP), which helps blood vessels relax. Omapatrilat demonstrated greater reduction in blood pressure than the ACE inhibitor lisinopril in individuals with salt-sensitive hypertension who typically do not respond well to ACE inhibitors.
Vanlev Absorption
The absolute oral bioavailability of omapatrilat is 20% to 30% and the absorption is not affected by food intake.
Vanlev side effects and Toxicity
Side effects include hyperkalemia, cough, hypotension, increased SrCr, and dizziness. Dizziness, diarrhea, vision disturbance, hypotension and angioedema
Vanlev Patient Information
No information avaliable
Vanlev Organisms Affected
Humans and other mammals
