Omalizumab
Omalizumab Brand names, Omalizumab Analogs
Omalizumab Brand Names Mixture
- No information avaliable
Omalizumab Chemical_Formula
C6450H9916N1714O2023S38
Omalizumab RX_link
http://www.rxlist.com/cgi/generic3/xolair.htm
Omalizumab fda sheet
Omalizumab msds (material safety sheet)
Omalizumab Synthesis Reference
Sequence in Presta et al., J. of Immunol. 151, 2623 1993
Omalizumab Molecular Weight
145058.2
Omalizumab Melting Point
61 oC (FAB fragment), 71 oC (whole mAb) - Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
Omalizumab H2O Solubility
No information avaliable
Omalizumab State
Liquid
Omalizumab LogP
-0.432
Omalizumab Dosage Forms
Powder for solution
Omalizumab Indication
For treatment of asthma caused by allergies
Omalizumab Pharmacology
Xolair inhibits the binding of IgE to the high-affinity IgE receptor (FceRI) on the surface of mast cells and basophils. Reduction in surface-bound IgE on FceRI-bearing cells limits the degree of release of mediators of the allergic response. Xolair is used to treat severe, persisten asthma.
Omalizumab Absorption
No information avaliable
Omalizumab side effects and Toxicity
No information avaliable
Omalizumab Patient Information
No information avaliable
Omalizumab Organisms Affected
Humans and other mammals
