Xolair (Genentech Inc)
Xolair (Genentech Inc) Brand names, Xolair (Genentech Inc) Analogs
Xolair (Genentech Inc) Brand Names Mixture
- No information avaliable
Xolair (Genentech Inc) Chemical_Formula
C6450H9916N1714O2023S38
Xolair (Genentech Inc) RX_link
http://www.rxlist.com/cgi/generic3/xolair.htm
Xolair (Genentech Inc) fda sheet
Xolair (Genentech Inc) msds (material safety sheet)
Xolair (Genentech Inc) Synthesis Reference
Sequence in Presta et al., J. of Immunol. 151, 2623 1993
Xolair (Genentech Inc) Molecular Weight
145058.2
Xolair (Genentech Inc) Melting Point
61 oC (FAB fragment), 71 oC (whole mAb) - Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
Xolair (Genentech Inc) H2O Solubility
No information avaliable
Xolair (Genentech Inc) State
Liquid
Xolair (Genentech Inc) LogP
-0.432
Xolair (Genentech Inc) Dosage Forms
Powder for solution
Xolair (Genentech Inc) Indication
For treatment of asthma caused by allergies
Xolair (Genentech Inc) Pharmacology
Xolair inhibits the binding of IgE to the high-affinity IgE receptor (FceRI) on the surface of mast cells and basophils. Reduction in surface-bound IgE on FceRI-bearing cells limits the degree of release of mediators of the allergic response. Xolair is used to treat severe, persisten asthma.
Xolair (Genentech Inc) Absorption
No information avaliable
Xolair (Genentech Inc) side effects and Toxicity
No information avaliable
Xolair (Genentech Inc) Patient Information
No information avaliable
Xolair (Genentech Inc) Organisms Affected
Humans and other mammals
