Novobiocin
Brand names,
Novobiocin
Analogs
Novobiocin
Brand Names Mixture
- Albacillin Suspension (Novobiocin (Novobiocin Sodium) + Penicillin G Procaine)
- Delta-Albaplex Tablets (Novobiocin (Novobiocin Sodium) + Prednisolone + Tetracycline Hydrochloride)
- Novodry Plus Suspension (Novobiocin (Novobiocin Sodium) + Penicillin G Procaine)
- Special Formula 17900-Forte Suspension (Dihydrostreptomycin (Dihydrostreptomycin Sulfate) + Hydrocortisone Acetate + Hydrocortisone Sodium Succinate + Novobiocin (Novobiocin Sodium) + Penicillin G Procaine + Polymyxin B Sulfate)
Novobiocin
Chemical_Formula
C31H36N2O11
Novobiocin
RX_link
No information avaliable
Novobiocin
fda sheet
Novobiocin
msds (material safety sheet)
Novobiocin
Synthesis Reference
No information avaliable
Novobiocin
Molecular Weight
612.624 g/mol
Novobiocin
Melting Point
No information avaliable
Novobiocin
H2O Solubility
Insoluble
Novobiocin
State
Solid
Novobiocin
LogP
2.737
Novobiocin
Dosage Forms
Drug premix; Suspension
Novobiocin
Indication
For the treatment of infections due to staphylococci and other susceptible organisms
Novobiocin
Pharmacology
Novobiocin is an aminoglycoside antibiotic. Aminoglycosides work by binding to the bacterial 30S ribosomal subunit, causing misreading of t-RNA, leaving the bacterium unable to synthesize proteins vital to its growth. Aminoglycosides are useful primarily in infections involving aerobic, Gram-negative bacteria, such as Pseudomonas, Acinetobacter, and Enterobacter. In addition, some mycobacteria, including the bacteria that cause tuberculosis, are susceptible to aminoglycosides. Infections caused by Gram-positive bacteria can also be treated with aminoglycosides, but other types of antibiotics are more potent and less damaging to the host. In the past the aminoglycosides have been used in conjunction with penicillin-related antibiotics in streptococcal infections for their synergistic effects, particularly in endocarditis. Aminoglycosides are mostly ineffective against anaerobic bacteria, fungi and viruses.
Novobiocin
Absorption
No information avaliable
Novobiocin
side effects and Toxicity
No information avaliable
Novobiocin
Patient Information
No information avaliable
Novobiocin
Organisms Affected
Enteric bacteria and other eubacteria