Novobiocinum [Inn-Latin]
Brand names,
Novobiocinum [Inn-Latin]
Analogs
Novobiocinum [Inn-Latin]
Brand Names Mixture
- Albacillin Suspension (Novobiocin (Novobiocin Sodium) + Penicillin G Procaine)
- Delta-Albaplex Tablets (Novobiocin (Novobiocin Sodium) + Prednisolone + Tetracycline Hydrochloride)
- Novodry Plus Suspension (Novobiocin (Novobiocin Sodium) + Penicillin G Procaine)
- Special Formula 17900-Forte Suspension (Dihydrostreptomycin (Dihydrostreptomycin Sulfate) + Hydrocortisone Acetate + Hydrocortisone Sodium Succinate + Novobiocin (Novobiocin Sodium) + Penicillin G Procaine + Polymyxin B Sulfate)
Novobiocinum [Inn-Latin]
Chemical_Formula
C31H36N2O11
Novobiocinum [Inn-Latin]
RX_link
No information avaliable
Novobiocinum [Inn-Latin]
fda sheet
Novobiocinum [Inn-Latin]
msds (material safety sheet)
Novobiocinum [Inn-Latin]
Synthesis Reference
No information avaliable
Novobiocinum [Inn-Latin]
Molecular Weight
612.624 g/mol
Novobiocinum [Inn-Latin]
Melting Point
No information avaliable
Novobiocinum [Inn-Latin]
H2O Solubility
Insoluble
Novobiocinum [Inn-Latin]
State
Solid
Novobiocinum [Inn-Latin]
LogP
2.737
Novobiocinum [Inn-Latin]
Dosage Forms
Drug premix; Suspension
Novobiocinum [Inn-Latin]
Indication
For the treatment of infections due to staphylococci and other susceptible organisms
Novobiocinum [Inn-Latin]
Pharmacology
Novobiocin is an aminoglycoside antibiotic. Aminoglycosides work by binding to the bacterial 30S ribosomal subunit, causing misreading of t-RNA, leaving the bacterium unable to synthesize proteins vital to its growth. Aminoglycosides are useful primarily in infections involving aerobic, Gram-negative bacteria, such as Pseudomonas, Acinetobacter, and Enterobacter. In addition, some mycobacteria, including the bacteria that cause tuberculosis, are susceptible to aminoglycosides. Infections caused by Gram-positive bacteria can also be treated with aminoglycosides, but other types of antibiotics are more potent and less damaging to the host. In the past the aminoglycosides have been used in conjunction with penicillin-related antibiotics in streptococcal infections for their synergistic effects, particularly in endocarditis. Aminoglycosides are mostly ineffective against anaerobic bacteria, fungi and viruses.
Novobiocinum [Inn-Latin]
Absorption
No information avaliable
Novobiocinum [Inn-Latin]
side effects and Toxicity
No information avaliable
Novobiocinum [Inn-Latin]
Patient Information
No information avaliable
Novobiocinum [Inn-Latin]
Organisms Affected
Enteric bacteria and other eubacteria