Antibiotic Pa-93
Brand names,
Antibiotic Pa-93
Analogs
Antibiotic Pa-93
Brand Names Mixture
- Albacillin Suspension (Novobiocin (Novobiocin Sodium) + Penicillin G Procaine)
- Delta-Albaplex Tablets (Novobiocin (Novobiocin Sodium) + Prednisolone + Tetracycline Hydrochloride)
- Novodry Plus Suspension (Novobiocin (Novobiocin Sodium) + Penicillin G Procaine)
- Special Formula 17900-Forte Suspension (Dihydrostreptomycin (Dihydrostreptomycin Sulfate) + Hydrocortisone Acetate + Hydrocortisone Sodium Succinate + Novobiocin (Novobiocin Sodium) + Penicillin G Procaine + Polymyxin B Sulfate)
Antibiotic Pa-93
Chemical_Formula
C31H36N2O11
Antibiotic Pa-93
RX_link
No information avaliable
Antibiotic Pa-93
fda sheet
Antibiotic Pa-93
msds (material safety sheet)
Antibiotic Pa-93
Synthesis Reference
No information avaliable
Antibiotic Pa-93
Molecular Weight
612.624 g/mol
Antibiotic Pa-93
Melting Point
No information avaliable
Antibiotic Pa-93
H2O Solubility
Insoluble
Antibiotic Pa-93
State
Solid
Antibiotic Pa-93
LogP
2.737
Antibiotic Pa-93
Dosage Forms
Drug premix; Suspension
Antibiotic Pa-93
Indication
For the treatment of infections due to staphylococci and other susceptible organisms
Antibiotic Pa-93
Pharmacology
Novobiocin is an aminoglycoside antibiotic. Aminoglycosides work by binding to the bacterial 30S ribosomal subunit, causing misreading of t-RNA, leaving the bacterium unable to synthesize proteins vital to its growth. Aminoglycosides are useful primarily in infections involving aerobic, Gram-negative bacteria, such as Pseudomonas, Acinetobacter, and Enterobacter. In addition, some mycobacteria, including the bacteria that cause tuberculosis, are susceptible to aminoglycosides. Infections caused by Gram-positive bacteria can also be treated with aminoglycosides, but other types of antibiotics are more potent and less damaging to the host. In the past the aminoglycosides have been used in conjunction with penicillin-related antibiotics in streptococcal infections for their synergistic effects, particularly in endocarditis. Aminoglycosides are mostly ineffective against anaerobic bacteria, fungi and viruses.
Antibiotic Pa-93
Absorption
No information avaliable
Antibiotic Pa-93
side effects and Toxicity
No information avaliable
Antibiotic Pa-93
Patient Information
No information avaliable
Antibiotic Pa-93
Organisms Affected
Enteric bacteria and other eubacteria